Synthesis of novel formulations for brain pathologies

Synthesis of novel formulations for brain pathologies

Achieved the synthesis of novel engineered cellular vesicles from brain endothelial cells[1] and 2-(4′-Aminophenyl) benzothiazole-liposomes [2]  that have high brain targeting ability (in vitro and in vivo) [1], and Inhibit Aβ1-42Fibril Formation [2]


Marazioti, A., Papadia, K., Kannavou, M., (…), Stathopoulos, G.T., Antimisiaris, S.G. 2019 Cellular vesicles: New insights in engineering methods, interaction with cells and potential for brain targeting Open Access Journal of Pharmacology and Experimental Therapeutics 370(3), pp. 772-785

Mourtas, S., Mavroidi, B., Marazioti, A., (…), Pelecanou, M., Antimisiaris, S.G. 2020 Liposomes Decorated with 2-(4′-Aminophenyl)benzothiazole Effectively Inhibit Aβ1-42Fibril Formation and Exhibit in Vitro Brain-Targeting Potential Biomacromolecules 21(12), pp. 4685-4698