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Associate Researcher, FORTH/ICE-HT,
Greece
Adjunct Assistant Professor, Dept. of Chemical Engineering,
University of Maryland, College Park, MD 20742 USA |
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| Tel. : +30 2610-965 249 Email:
mklapa@iceht.forth.gr
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Education:
Diploma, Chemical Engineering, National Technical University of Athens
(N.T.U.A.), Greece, 1995
Ph.D., Chemical Engineering, Massachusetts Institute of Technology (MIT),
Cambridge, MA 02139, USA, 2001
Postdoctoral Research Associate, Chemical Engineering, Massachusetts
Institute of Technology (MIT), Cambridge, MA 02139, USA, 2001
Postdoctoral Fellow, Functional Genomics, The Institute for Genomics
Research (TIGR), Rockville, MD 20850, USA, 2002
Previous Employment/Occupation:
Assistant Professor, Dept. of Chemical Engineering, UMCP, USA, 08/02
- present
Adjunct Assistant Professor, Dept. of Chemical Engineering, UMCP, USA,
12/01 – 08/02
Postdoctoral Fellow, The Institute for Genomic Research, USA, 01/02
– 08/02
Postdoctoral Research Associate, Dept. of Chemical Engineering, MIT,
USA, 10/01 – 12/01
Graduate Research Assistant, Dept. of Chemical Engineering, MIT, USA,
09/95 – 09/01
Diploma Thesis, Dept. Chemical Engineering, N.T.U. Athens, Greece, 02/95
– 07/95
Summer Trainee, Von Karman Institute for Fluid Dynamics, Rhode-St-Genese,
Belgium, 07/94 - 09/94
Summer Intern, Hellenic Cement Research Center, Hercules Group (AGET),
Likovrissi Attikis, Greece, 07/1993 - 09/1993
Research Activities:
Metabolic Engineering with Emphasis in Metabolic Flux Analysis and
Metabolic Profiling (Metabolomics)
Quantitative Systems Biology
Functional genomics
Mathematical modelling of biological networks
Participation in Research Projects:
Is currently directing 1 project at UMCP, USA funded by the US National
Science Foundation on quantitative systems biology in collaboration
with Dr. John Quackenbush at The Institute for Genomic Research (TIGR),
MD, USA.
Is actively participating as FORTH-ICE-HT researcher in the Nano2Life
European Network of Excellence (www.nano2life.org).
Publications:
2 chapters in books, 7 + 1 (in Press) refereed journal papers, 1 paper
in refereed conference proceedings
Conference Participation / Attendance:
17 presentations/posters in US and International conferences. 6 invited
seminars/lectures at universities and conferences.
- Co-organizer of the Topical Conference in Bioinformatics and Functional
Genomics, AIChE Annual Meeting, 2002-2003
- Chair of the session Bioinformatics and Functional Genomics II:
Metabolic Engineering and Disease Marker Identification, Bioinformatics
Topical Conference, AIChE Annual Meeting, November 2003, San Francisco,
CA
- Chair of the session Metabolic Engineering and Bioinformatics I:
Perspectives and Applications, Bioinformatics Topical Conference,
AIChE Annual Meeting, 3-8 November 2002, Indianapolis, Indiana
- Chair of the session Metabolic Engineering and Bioinformatics II:
Scope and Future of Metabolic Engineering (panel discussion), Bioinformatics
Topical Conference, AIChE Annual Meeting, 3-8 November 2002, Indianapolis,
Indiana
- Co-chair of the workshop on experimental techniques and the challenge
of multiplexing in Metabolic Engineering Conference IV, October 2002,
Tuscany, Italy
Teaching Activities:
- Developed and taught new high-level undergraduate and graduate
course in Advances in Metabolic Engineering and Quantitative Systems
Biology at UMCP, USA (ENCH468H - ENCH762), Spring 2003;
- Taught the engineering freshman course “Introduction
to Engineering Design” at UMCP, USA (ENES 100), Fall 2003;
- Is Developing and teaching a graduate course in Bioinformatics
in the context of the interdisciplinary Master’s program in
Mathematical Modeling in Modern Technologies and Economics (http://www.math.ntua.gr/greek/postgraduate/new_progr/index.htm)
at the National Technical University of Athens (NTUA), Greece, Spring
2004 ;
Professional Affiliations
Associate Member of American Institute of Chemical Engineers (AIChE);
Member of the American Chemical Society (ACS);
Member of the American Society of Plant Biologists (ASPB);
Member of the American Association for the Advancement of Science (AAAS);
Associate Student Member of the Sigma Xi Research Society;
Member of the Technical Chamber of Greece
Prizes/Honours
| 1991-1994 |
Scholarship from the Hellenic Federal
Fellowship Foundation for outstanding academic performance ; |
| 1996 |
Prize from the Technical Chamber of Greece
for outstanding academic performance; |
| 1997 |
Fellowship from “Empeirikeio”
Foundation, Athens, Greece, to study in US; |
| 1997 |
Prize from NTUA, Greece for graduating first
in the Chemical Engineering class of 1995 |
| 1997 |
Associate Student Member of the MIT Chapter
of Sigma Xi Research Society; |
| 2000 |
Travel grant (3 awarded) from the Bioinformatics
and Genomics Topical Conference, 2000 AIChE Annual Meeting, Los
Angeles, CA, 12-17 November 2000 |
Selected Publications:
- Klapa, M.I. and Quackenbush J. 2003. The Quest for the Mechanisms
of Life Biotechnol Bioeng. 84:739-42.
- Klapa, M.I., Aon, J.C. and Stephanopoulos, Gregory. 2003. Systematic
quantification of complex metabolic flux networks using stable isotopes
and mass spectrometry Eur J Biochem 270: 3525-42.
- Klapa, MI, Aon, J.C. and Stephanopoulos, Gregory. 2003. Using ion
trap Mass Spectrometry in combination with gas chromatography for
high-resolution metabolic flux determination. Biotechniques 34: 832-6,
838, 840 passim.
- Klapa MI, Park SM, Sinskey AJ, Stephanopoulos GN. 1999. Metabolite
and isotopomer balancing in the analysis of metabolic cycles: I. Theory.
Biotechnol Bioeng. 62: 375-391.
- Park SM, Klapa MI, Sinskey AJ, Stephanopoulos GN. 1999. Metabolite
and isotopomer balancing in the analysis of metabolic cycles: II.
Applications. Biotechnol Bioeng. 62: 392-401.
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