Antimisiaris Sophia

	Professor Department of Pharmacy, School of Health Sciences, University of Patras, Greece
Tel. : +30 2610-969 332   Email: santimis@upatras.gr
Last updated: March 2010

Education:

1980-1984: Department of Pharmacy, School of Health Sciences, University of Athens, Greece, Degree: Bpharm (8.4/10)
1984-1988: Department of Pharmacy, School of Health Sciences, University of Athens, Greece, Degree: PhD (Biopharmaceutics)
1997: Pharmacist License

Previous Employment/Occupation:

2002-2009: Associate Professor, Department of Pharmacy, University of Patras, Greece.
1993-2002: Assistant Professor, Department of Pharmacy, University of Patras, Greece.
1992-1993: Visiting Professor, School of Pharmacy, University of London, UK
1989-1993: Lecturer, Department of Pharmacy, University of Patras, Greece.
1988-1989 / 1990: PostDoc fellow / Visiting Professor, School of Pharmacy, University of South California (USC), Los Angeles, USA.

Research Activities:

• Biopharmaceutics and Pharmacokinetics: Improving Drug Biodistribution and Pharmacokinetics through Advances Drug Delivery System Design
• Nanomedicines: Liposomal or Nanoparticulate systems for Controlled Drug (or Vaccine) Delivery and/or Targeting
• Application of novel lipid vesicles (Arsonoliposomes) in Anticancer / Antiparasitic Therapeutics
• Novel Controlled-(Release)-Drug-Releasing Stents
• Ocular, Alveolar and Vaginal Drug Delivery
• Application of Liposomes in Analytical Techniques
• Nanoparticles for Alzheimers Disease / Targeting the Brain

Participation in Research Projects:

1989-: Participation as coordinator and/or PI in 2 National (GSRT & Ministry of Education) funded and 8 European programs, including Marie-Curie mobility - training project (FP6), Socrates mobility and Intensive Program Training Projects (LLLP), Integrated Project (FP6-Health & FP7-NMP), Interreg program and industry-funded projects.

Publications:

65 Papers in peer-reviewed journals, 14 Invited Papers & Reviews or Chapters in Book Series, 90 Abstracts in proceeding of international conferences, 6 Papers in Greek Scientific Journals, 1 World patent and 2 Greek patents.

Conference Participation/Attendance:

Participation in more than 50 International conferences or educational workshops, and more than 15 National conferences, Invited speaker in more than 20 National and International scientific or educational meetings / workshops.

Teaching:

1989- Undergraduate Program (Pharmacy Dept): Biopharmaceutics and Pharmacokinetics (+Practical course) Pharmaceutical Technology: Pre-Formulation / Design and Preparation of Drug Formulation.(+Practical course)
1995 - Postgraduate Program (Pharmacy Dept): Applied Pharmacokinetics, Determination of Drugs in Biological Fluids, Pharmaceutical Statistics, Advanced-Novel Pharmaceutical Formulations (Liquid, Semi-Solid, Solid)
2000 - Postgraduate Program (School of Medicine): Pharmacokinetic Modeling / Modulating Drug Pharmacokinetics by Advanced Drug Delivery Systems
For the Socrates Educational Program "Novel Drug Delivery Systems: 10-day Workshop entitled: Liposome Technology and Applications in Therapeutics/Nanomedicines (1997-98, 1999-2000, 2003, 2008).

Professional Activities:

Referee of 28 Pharmaceutical and related Scientific journals. Participation in three Research Proposal Evaluator panels (& Panel Rapporateur), European Commission, Research Directorate, 2004-2008 (2) and 2008-2013 (1). Evaluator for the Spanish Ministry of Development and Research (after invitation), Evaluatores, 2006 & 2008, and Israel Research Foundation (2010). President of the Western-Greece Committee for evaluation of Pharmacy Technicians (2001-). Evaluator for the National Foundation of Drugs (EOF) for Clinical Studies and Formulation Bioequivalence Studies (2000-). Member of Scientific Committee of the International Conference of European Association of Pharma Biotechnology [EAPB] (2004). Member of Scientific Advisory Board Europe, of New Drugs, official publication of EAPB (2004). Associate Editor of J. Biomedical Nanotechnology. Invited editor of JBN Special Issue on Nanomedicines (2008). Member of Editorial Board of Journal of Pharmacy and BioAllied Sciences (2010) and Journal of Drug Delivery (2010). Member of the Senate, Univ. of Patras (2004-5). Member of the Graduate Studies committee, Dept. of Pharmacy, Univ. of Patras (1998-). Coordinator of the Socrates mobility Program for the Dept. of Pharmacy, Univ. of Patras (1998-).

Professional Affiliations:

• Panhellenic Association of Pharmacists
• APGI/APV (Association de Pharmacie Galenique Industrielle)
• European Federation of Pharmaceutical Scientists (EUFEPS)
• Controlled Release Society (CRS)
• CRS -Greek Chapter [President 1999-2001]
• International Liposome Society (ILS)
• AAPS -American Association of Pharmaceutical Scientists
• Galenos Network for novel Drug delivery Exploitation and Education

Prizes/Honours:

1980-1984: Scholarships from Greek State Scholarships’ Foundation (IKY) for outstanding performance during undergraduate studies (Ranking in top 5% of class)

Selected Publications:

• G. Koromila, G. Michanetzis, Y.F. Missirlis, S.G.Antimisiaris, Heparin incorporating liposomes as a delivery system of heparin from PET-covered metallic stents: Effect on haemocompatibility, Biomaterials, 27:12, 2525-2533, 2006
• M. Zaru, S. Mourtas, P. Klepetsanis, A.M. Fadda and S.G.Antimisiaris, Liposomes for drug delivery to the lungs after nebulization. Eur. J. Pharmaceutics & Biopharmaceutics, 67 (3), pp. 655-666, 2007
• P. Zagana, M. Haikou, P. Klepetsanis, E. Giannopoulou, P.V. Ioannou, S.G. Αntimisiaris, In vivo distribution of arsonoliposomes: Effect of vesicle lipid composition,  Int. J. Pharm, 347 (1-2), pp. 86-92, 2008
• P. Zagana, M. Haikou, E. Giannopoulou, P.V. Ioannou, S.G. Antimisiaris, Arsonoliposome Interaction with cells in culture. Effect of pegylation and lipid composition. Invited contribution, J. Mol. Nutr. Food Res. 53, 592 - 599 (2009)
• S. Mourtas, C. Aggelopoulos, P. Klepetsanis, C. Tsakiroglou, S.G. Antimisiaris, "Complex gel formulations for topical drug administration: Rheological properties and aging", Invited contribution, Langmuir, 25: 15 8480-8488 2009
• S.G. Antimisiaris, "Preparation of DRV liposomes", From Methods in Molecular Biology (Clifton, N.J.) (2010), 605, 51-75. ISBN: 978-1-60327-359-6